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Journal Articles

 

27.  Discovery and Structure-Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual Screening

S.N. Dighe^, G.S. Deora^, E. De la Mora, F. Nachon, S. Chan, M.-O. Parat, X. Brazzolotto, B.P. Ross

Journal of Medicinal Chemistry 2016,

doi:10.1021/acs.jmedchem.6b00356

^ These authors contributed equally to this work

 

26.    Metal chelation, radical scavenging and inhibition of Aβ42 fibrillation by food constituents in relation to Alzheimer’s disease

S. Chan^, S. Kantham^, V.M. Rao, M.K. Palanivelu, H.L. Pham, P.N. Shaw, R.P. McGeary, B.P. Ross

Food Chemistry 2016, 199, 185-194

doi:10.1016/j.foodchem.2015.11.118

^ These authors contributed equally to this work

 

25.    "Click" Assembly of Glycoclusters and Discovery of a Trehalose Analogue that Retards Aβ40 Aggregation and Inhibits Aβ40-induced Neurotoxicity

H. Rajaram, M.K. Palanivelu, T.V. Arumugam, V.M. Rao, P.N. Shaw, R.P. McGeary, B.P. Ross

Bioorganic & Medicinal Chemistry Letters 2014, 24, 4523-4528

doi:10.1016/j.bmcl.2014.07.077

 

24.   Cyclodextrin-crosslinked poly(acrylic acid): Adhesion and controlled release of diflunisal and fluconazole from solid dosage forms

M.J. Kutyla, M.W. Boehm, J.R. Stokes, P.N. Shaw, N.M. Davies, R.P. McGeary, J. Tuke, B.P. Ross

AAPS PharmSciTech 2013, 14, 301-311

doi:10.1208/s12249-012-9903-3

 

23. Cyclodextrin-crosslinked poly(acrylic acid): Synthesis, physicochemical characterization and controlled release of diflunisal and fluconazole from hydrogels

M.J. Kutyla, L.K. Lambert, N.M. Davies, R.P. McGeary, P.N. Shaw, B.P. Ross

International Journal of Pharmaceutics 2013, 444, 175-184

doi:10.1016/j.ijpharm.2013.01.005

 

22.   Enzyme-Responsive Controlled Release of Covalently Bound Prodrug from Functional Mesoporous Silica Nanospheres

A. Popat, B.P. Ross, J.Liu, S. Jambhrunkar, F. Kleitz, S.Z. Qiao

Angewandte Chemie International Edition 2012, 51, 12486-12489

doi:10.1002/anie.201206416

 

21.   2-Mercaptobenzothiazole and its Derivatives: Syntheses, Reactions and Applications

F.-L. Wu, W.M. Hussein, B.P. Ross, R.P. McGeary

Current Organic Chemistry 2012, 16, 1555-1580

doi:10.2174/138527212800840964

 

20.    Phytochemical Study of Fagraea spp. Uncovers A New Terpene Alkaloid with Anti-Inflammatory Properties

S. Suciati, L.K. Lambert, B.P. Ross, M.A. Deseo, M.J. Garson

Australian Journal of Chemistry 2011, 64, 489-494

doi:10.1071/CH10421

 

19.     New Methodology for the Conversion of Epoxides to Alkenes

F.-L. Wu, B.P. Ross, R.P. McGeary

European Journal of Organic Chemistry 2010, 10, 1989-1998

doi:10.1002/ejoc.200901264

 

18.   Synthetic Approaches to Functionalized Lipids for Protein Monolayer Crystallizations

W.M. Hussein, B.P. Ross, M.J. Landsberg, B. Hankamer, R.P. McGeary

Current Organic Chemistry 2009, 13, 1378-1405

doi:10.2174/138527209789055081

 

17.   Efficient Manual Fmoc Solid-Phase Synthesis of the N-Terminal Segment of Surfactant Protein B (SP-B(1-25))

S. Ramli, I.R. Gentle, B.P. Ross

Protein & Peptide Letters 2009, 16, 810-814

doi:10.2174/092986609788681706

Link to the post-print manuscript

 

16.    Synthesis of cationic derivatives of Quil A and the preparation of cationic immune-stimulating complexes (ISCOMs)

H.L. Pham, B.P. Ross, R.P. McGeary, P.N. Shaw, N.M. Davies

International Journal of Pharmaceutics 2009 , 376, 123-133

doi:10.1016/j.ijpharm.2009.04.011

 

15.     An "inside-out" approach to suramin analogues

R.P. McGeary, A.J. Bennett, Q.B. Tran, J. Prins, B.P. Ross

Tetrahedron 2009, 65, 3990-3997

doi:10.1016/j.tet.2009.03.033

 

14.  Synthesis of Nickel-Chelating Fluorinated Lipids for Protein Monolayer Crystallizations

W.M. Hussein, B.P. Ross, D. Lévy, M.J. Landsberg, B. Hankamer, R.P. McGeary

Journal of Organic Chemistry 2009, 74, 1473-1479

doi:10.1021/jo802651p

 

13.     Suramin: Clinical Uses and Structure-Activity Relationships

R.P. McGeary, A.J. Bennett, Q.B. Tran, K.L. Cosgrove, B.P. Ross

Mini-Reviews in Medicinal Chemistry 2008, 8, 1384-1394

doi:10.2174/138955708786369573

 

12.     N-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl (N-Dde) Lipoamino Acids

B.P. Ross, R.A. Falconer, I. Toth

Molbank 2008, M566

doi:10.3390/M566

 

11.     Caco-2 Cell Permeability and Stability of Two D-Glucopyranuronamide Conjugates of Thyrotropin-Releasing Hormone

S.T. Wessling, B.P. Ross, Y. Koda, J.T. Blanchfield, I. Toth

Bioorganic & Medicinal Chemistry 2007, 15, 4946-4950

doi:10.1016/j.bmc.2007.04.042

 

10.     Rhodamine B Pentyl Ester and its Methyl, Ethyl, Propyl, and Butyl Homologues

J.A. Ross, B.P. Ross, K.L. Cosgrove, H. Rubinsztein-Dunlop, R.P. McGeary

Molbank 2006, M515

doi:10.3390/M515

 

9.       Saponins from Quillaja saponaria Molina: Isolation, Characterization and Ability to Form Immuno Stimulatory Complexes (ISCOMs)

H.L. Pham, B.P. Ross, R.P. McGeary, P.N. Shaw, A.K. Hewavitharana, N.M. Davies

Current Drug Delivery 2006, 3, 389-397

doi:10.2174/156720106778559092

 

8.     Determination of the Anomeric Configurations of 2,3,4,6-Tetra-O-Acetyl-D-Mannopyranosyl Azide

K.L. Cosgrove, P.V. Bernhardt, B.P. Ross, R.P. McGeary

Australian Journal of Chemistry 2006, 59, 473-476

doi:10.1071/CH06157

 

7.       Facile Synthesis of Rhodamine Esters Using Acetyl Chloride in Alcohol Solution

          J.A. Ross, B.P. Ross, H. Rubinsztein-Dunlop, R.P. McGeary

Synthetic Communications 2006, 36, 1745-1750

doi:10.1080/00397910600616818

 

6.      Polycationic lipophilic-core dendrons as penetration enhancers for the oral administration of low molecular weight heparin

P.Y. Hayes, B.P. Ross, B.G. Thomas, I. Toth

Bioorganic & Medicinal Chemistry 2006, 14, 143-152

doi:10.1016/j.bmc.2005.08.004

 

5.       Gastrointestinal Absorption of Heparin by Lipidization or Coadministration with Penetration Enhancers

B.P. Ross, I. Toth

Current Drug Delivery 2005, 2, 277-287

doi:10.2174/1567201054367968

 

4.      Design, Synthesis, and Evaluation of a Liposaccharide Drug Delivery Agent: Application to the Gastrointestinal Absorption of Gentamicin

B.P. Ross,  S.E. DeCruz, T.B. Lynch, K. Davis-Goff, I. Toth

Journal of Medicinal Chemistry 2004, 47, 1251-1258

doi:10.1021/jm030474j

 

3.       Micellar Aggregation and Membrane Partitioning of Bile Salts, Fatty Acids, Sodium Dodecyl Sulfate, and Sugar-Conjugated Fatty Acids: Correlation with Hemolytic Potency and Implications for Drug Delivery

B.P. Ross, A.C. Braddy, R.P. McGeary, J.T. Blanchfield, L. Prokai, I. Toth

Molecular Pharmaceutics 2004, 1, 233-245

doi:10.1021/mp049964d

 

2.     Determination of transport in the Caco-2 cell assay of compounds varying in lipophilicity using LC-MS: enhanced transport of Leu-enkephalin analogues

A.K. Wong, B.P. Ross, Y.-N. Chan, P. Artursson, L. Lazorova, A. Jones, I. Toth

European Journal of Pharmaceutical Sciences 2002, 16, 113-118

doi:10.1016/S0928-0987(02)00078-7

 

1.     Halogenated Terpenoids. XXXII. Pentabromides from Limonene -Two 1,2,8,9,9-Pentabromo-p-menthanes

P.V. Bernhardt, R.M. Carman, B.P. Ross

Australian Journal of Chemistry 2000, 53, 611-614

doi:10.1071/CH00022

 

Patents

 

Oral drug delivery systems comprising ionic complexes including mono- or oligosaccharide, lipidic moiety, and optionally a linker and/or a spacer.

Toth I, Falconer R, De Cruz S E, McGeary R P, Ross B P (2007)

US7312194-B2; US20040176281-A1; WO2002053572-A1

[Continuation-in-part of Appl. No. PCT/AU02/5].

 

New amide-linked mono, di and tri-saccharide-lipoamino acid complex useful in drug delivery

Toth I, Falconer R, De Cruz S E, McGeary R P, Ross B P (2002)

WO200253572-A; WO200253572-A1; AU2002216843-A1; US2004176281-A1

 

 

  

Latest News

 

2 April 2013: Welcome Mr Suresh Veliyath (PhD candidate). Suresh has a masters degree in pharmaceutical chemistry from Rajiv Gandhi University, Bangalore. He worked as a project assistant at the Indian Institute of Science (IISC) Bangalore and as a faculty member at MIPS Hyderabad, before joining the Ross Group. Suresh's PhD project is focused on AD drug discovery.

 

6 February 2013: Welcome Mr Girdhar Singh Deora (PhD candidate). Giri completed a MPharm from Rajiv Gandhi Technological University, Bhopal in 2009. Prior to joining the Ross Group, Giri worked as a research associate at Rajiv Gandhi Technological University (2010-11) and at Dr Reddy's Institute of Life Sciences, Hyderabad (2011-13). Giri's PhD project is in the field of AD drug discovery.

 

10 January 2013: Welcome Mr Edward Lee (PhD candidate). Eddy completed a BPharm (2010) and postgraduate honours (2012) degrees at UQ and he was awarded an APA scholarship for his PhD project to develop anti-viral nanoparticles.

 

1 November 2012: Welcome Mr Satish Dighe (PhD candidate). Satish was awarded an MPharm in 2009 from Pune University, and worked as a research chemist at Zydus-Cadila Healthcare Limited (2009-11; Ahmedabad) and as a research assistant at the Birla Institute of Techology and Science (2011-12; Pilani), before joining the Ross Group. The topic of Satish's PhD project is AD drug discovery.

 

3 July 2012: Welcome Mr Srinivas Kantham (PhD candidate) who is funded by a prestigious Prime Minister's Australia Asia Incoming Postgraduate Award. For his PhD Srinivas is developing polyphenols as disease-modifying drugs for AD. Previously he worked as a research assistant at the Indian Institute of Chemical Technology (IICT) Hyderabad.

 

 

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Contact

 

Dr Ben Ross

 

Courier address:

School of Pharmacy,

The University of Queensland,

20 Cornwall Street,

Woolloongabba, Qld 4102,

Australia

 

Postal address:

School of Pharmacy,

The University of Queensland, Brisbane, Qld 4072, Australia

 

Phone: +61 7 334 61900

Fax: +61 7 334 61999

 

Email:

 

 

 

This web site was last updated on 16 December 2015. Copyright © 2006-2016 Benjamin P. Ross. Unless stated otherwise, this web site represents only the views of Benjamin P. Ross and not the views of The University of Queensland. Simple site map.